Crspy is expressed exclusively in males with particularly strong expression in testis and kidney. Expression analysis shows widespread expression of Crspx. Sequence comparison shows extensive divergence between the X and Y copy, but we found no significant positive selection on either gametolog. We also identified the X-chromosomal copy which unexpectedly maps to X1 (Crspx). Here, we report the identification and characterization of the mediator complex protein gametologs on platypus Y5 (Crspy). We analyzed sequences derived from Y-specific BAC clones to identify genes with potentially male-specific function. However, no gene has so far been described on any of the Y chromosome-specific regions. Recently, sequence information from autosomes, X chromosomes, and XY-shared pseudoautosomal regions has become available.

The basal lineage of monotremes features an extraordinarily complex sex chromosome system which has provided novel insights into the evolution of mammalian sex chromosomes. Bernard, Pascal Lim, Shu Ryan, Janelle Rosenkranz, Ruben Borodina, Tatiana Dohm, Juliane Himmelbauer, Heinz Harley, Vincent GrГјtzner, Frank Identification of mediator complex 26 (Crsp7) gametologs on platypus X1 and Y5 sex chromosomes: a candidate testis-determining gene in monotremes? Identification of mediator complex 26 (Crsp7) gametologs on platypus X1 and Y5 sex chromosomes: a.

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